PRAMOXINE HYDROCHLORIDE In 1953, a local pharmaceutical company produced a revolutionary anesthetic product named Pramoxine. It is also known as Pramoxine Hydrochloride and Pramocaine. Before that, dozens of anesthetic products were available, but why pramoxine hydrochloride got hype? It has low sensitivity and works excellently as an antipruritic. Most anti-itch creams not only treat the skin area from specific rash, sunburn, allergies, etc. but cause extreme sensitivity and irritation at the same time. But Pramoxine has a milder take on the treatment area. It stood out as the best local topical anesthetic product.
It works by numbing the area and being absorbed by the outer membrane. It calms the pain stimulus by decreasing the absorption of sodium ions via neuronal membranes resulting in the blockage of initiation and regulation of nerve impulses that produce pain stimulus. The sensitivity rate is low in humans, and the impression of the product is of low potency. It is an over-the-counter drug for hemorrhoids, sunburns, mild skin rashes, and sensitivity. Reduce eczema, insect bites, cuts, and minor burn wounds.
Important Things To Know About Pramoxine Hydrochloride
How Does Pramoxine Hydrochloride Work?
The mechanism of Pramoxine hydrochloride initiates by stopping neural membranes from absorbing through the sodium ions present in the standard bloodstream. This action will calm the membranal tissue and prevent the inhibition of ionic fluxes, which blocks ionic conduction. The signal of pain will be cut through the nerve impulse—resulting in potential numbness of the treatment area.
Moreover, the agents of Pramoxine hydrochloride will be easily absorbed through the mucous membrane. Drug dosage depends upon the blood flow rate and circulation speed in the targeted area. Also, the concentration of dosage reflects the time limit of drug exposure. It starts working after 2 to 3 minutes of application, and numbness lasts 8 to 9 hours, depending on the dosage concentration.
Is It Available Over the Counter (OTC)?
Yes, Pramoxine Hydrochloride is available over-the-counter hemorrhoidal, Rectal, vaginal, and topical. It is available in powder, creams, and gel form. It numbs the hemorrhoidal site and minimizes itching for a while. It can be introduced in the vagina as a suppository to calm internal itchiness and discomfort. However, this is prohibited for children of 2 years of age. It is a counter anti-itch product for minor cuts, sunburns, Psoriasis, and stinginess caused by poison ivy and oaks. Its concentration as an OTC is standard, i.e., 0.5% to 1%.
Is Pramoxine Hydrochloride an Anti Histamine?
No, Pramoxine Hydrochloride is not an anti-histamine. It is an essential antipruritic product and works excellently, leaving no severe harm to the epidermal layer. It relieves the skin from itching and mild pain.
Does Pramoxine Hydrochloride Have Side Effects?
Although Pramoxine Hydrochloride is user-friendly, it may cause side effects if handled with lousiness. If it is in spray form, the container must be air-tight to avoid the product’s evaporation and diminish the product’s concentration. Otherwise, it will cause mild irritation and redness and, in some cases, excite the itchiness. The proper attention to creams, gels, lotions, and powder containing hydrochloride pramoxine is significant because a slight change and delay will prolong the numbness and irregulate blood circulation.
Who Should Use Pramoxine Hydrochloride?
Pramoxine hydrochloride can be used by anyone suffering from the mild itch, rash, sting, or hemorrhoidal issues. It has a reputation as an OTC, but getting a prescription from a doctor is always advisable.
Can It Work With Other Skincare Ingredients?
Pramoxine hydrochloride is the derivative of hydrochloride salt that has the reputation of ripping off moisture from the skin. This will maintain the skin’s moisturizing barrier.
Can Pramoxine Hydrochloride Be Used on the Body?
Yes, Pramoxine Hydrochloride is best to use on the face and body. Wherever; the sunburn and mild itch are present, it will provide relief, whether in the vaginal area, Anal area, or any topical area of the body. The physician will direct the internal administration of the product. So far, Pramoxine Hydrochloride has a heroic reputation owing to fewer side effects and higher relief potency. It holds the position of the No.1 anti-itch product. It is safer for adults’ topical use, but a doctor’s advice is best for children.